The CDC recommends the following:
- A smallpox vaccination should be administered within two weeks of exposure to monkeypox.
- Cidofovir (Vistide), an antiviral drug, is suggested for patients with severe, life-threatening symptoms.
- Vaccinia immune globulin may be used, but efficacy of use has not been documented.
For severe symptoms, supportive measures such as mechanical ventilation may rarely be needed. Consultation with an infectious-diseases expert and the CDC is recommended